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5 Powerful Prayers for the Toxic People in Your Life

  • Whitney Hopler Crosswalk.com Contributing Writer
  • Updated Mar 26, 2024
5 Powerful Prayers for the Toxic People in Your Life

In a world filled with complex relationships, encountering toxic people is inevitable. These toxic relationships can drain your energy, damage your emotional well-being, and interfere with your spiritual growth. Yet, God calls you to relate to everyone with love. Through prayer, you can find strength, guidance, and healing for yourself and for the toxic people in your life. Jesus challenges you in Matthew 5:44: “But I tell you, love your enemies and pray for those who persecute you.” Even when it seems like toxic relationships are so bad that they’re beyond changing, God can make positive change happen. God can help you find peace as you deal with the stress of dealing with toxic people. He can also help them change, if they’re willing. No matter what, it’s worthwhile to pray for toxic relationships. Here are five powerful prayers for the toxic people in your life. 

Photo Credit: © Getty Images/fizkes 

  • friends holding hands

    1. Prayer for self-control and patience.

    Dear God, as I deal with toxic people, give me the strength to exercise self-control and patience with them. When I interact and talk with them, please empower me to respond with the fruit of your Holy Spirit that the Bible mentions in Galatians 5:22-23 – love, joy, peace, patience, kindness, goodness, faithfulness, gentleness, and self-control. Teach me your wisdom and guidance when I deal with people who upset me. When emotions run high and frustration threatens to overwhelm me, give me the clarity of mind to pause and seek your presence. Please remind me of your enduring patience and unfailing love.

    The Bible reveals in 2 Peter 3:9 about you: “The Lord is not slow in keeping his promise, as some understand slowness. Instead, he is patient with you, not wanting anyone to perish, but everyone to come to repentance.” Help me to extend that same patience to those who may hurt or mistreat me. Enable me to see beyond their actions and into their hearts, recognizing their brokenness and need for your healing touch. God, I confess my own weaknesses and limitations as a human being living in this fallen world. I acknowledge that, without your grace, I am prone to react impulsively and speak harshly – especially in situations where I’m stressed by difficult people. So, please send your Holy Spirit to work within me, helping me develop a spirit of self-control and patience that reflects your character. Give me the persistence to persevere in prayer, seeking your guidance and strength daily. May my response to toxic people show the reality of your Spirit at work in my life. Thank you, God. Amen. 

    Photo Credit: © Getty Images/Jacob Wackerhausen 

  • Women on couch arguing and upset setting boundaries conflict mother in law

    2. Prayer for boundaries and protection.

    Dear God, please give me the wisdom to recognize unhealthy patterns in my interactions and the courage to set boundaries that safeguard my emotional, mental, and spiritual well-being. Help me to follow your advice in Proverbs 4:23: “Above all else, guard your heart, for everything you do flows from it.” Please show me how to establish boundaries rooted in love and respect in my relationships with toxic people. God, you know every relationship in my life. You see the areas where boundaries are needed to protect me from harm and preserve my peace. Give me the discernment to identify these areas and the strength to communicate my boundaries effectively and assertively. Give me the strength to uphold these boundaries firmly, even in the face of resistance or manipulation. I realize that the process of setting and keeping boundaries with toxic people can be uncomfortable and even lead to more conflict in my relationships at first.

    So, I need your grace to have these conversations successfully. Help me to clearly communicate my boundaries with intentional kindness, recognizing the dignity and worth of everyone involved. God, please also protect me from the influence of harmful behaviors in my toxic relationships. Shield my heart from bitterness, resentment, and emotional manipulation. Give me the courage to prioritize my well-being and to honor the boundaries I’ve set, even when faced with pressure to compromise. Remind me that boundaries are an expression of self-love and self-respect – not selfishness or a lack of forgiveness. Help me to release any guilt or shame associated with setting boundaries, with the confidence that it is a healthy action to take. As I establish and maintain healthy boundaries, may they create space for healthier relationships in my life. Amen.

    Photo Credit: ©GettyImages/PixelsEffect 

  • people talking discussing interview conversation

    3. Prayer for graceful conversations.

    Dear God, please give me the grace to be graceful as in my conversations with toxic people. Help me to be compassionate and put into practice your advice in Ephesians 4:32: “Be kind and compassionate to one another, forgiving each other, just as in Christ God forgave you.” Please give me the wisdom to choose my words carefully. Help me to speak truth with love, seasoning my words with grace and humility. Let my words bring healing and encouragement. Help me follow your advice in Proverbs 15:1: “A gentle answer turns away wrath, but a harsh word stirs up anger.” Teach me how to listen well, with empathy and understanding. Make me “should be quick to listen, slow to speak and slow to become angry,” as you call me to in James 1:19.

    Open my ears to truly hear the pain and brokenness behind the words and actions of the difficult people in my life. Help me to set aside my own agenda and preconceptions, making space for genuine connection and dialogue without judgment. Please give me the humility to admit when I’m wrong and the courage to seek reconciliation when conflicts arise. God, I confess my tendency to react impulsively and speak without thinking. So, I surrender my words and actions to you, asking for your Holy Spirit to guide and empower me. Give me the strength to respond to toxic people with grace and wisdom. Help me to follow the example of Jesus, who spoke gracefully to everyone, no matter what.

    Photo Credit: ©GettyImages/PrathanChorruangsak 

  • 4. Prayer for forgiveness and reconciliation.

    4. Prayer for forgiveness and reconciliation.

    Dear God, I acknowledge the weight of bitterness and resentment that I carry in my heart toward those who have hurt me. I confess the struggle within me to release the grip of unforgiveness and to extend forgiveness as you have commanded. Yet, I know that forgiveness is not just a suggestion but a necessity for my own spiritual well-being and growth. Please send me the strength and courage to forgive those who have wronged me, just as you have forgiven me, as you call me to do in Colossians 3:13. Free me from the chains of resentment and bitterness. Fill my heart with your wonderful love, giving me the power to forgive freely, regardless of the depth of the pain I’ve suffered from toxic people. I give you my pain and trust your promise in Psalm 147:3, which says of you: “He heals the brokenhearted and binds up their wounds.”

    God, please strengthen me to let go of the past and embrace the freedom that comes from forgiveness. Help me to see those who have hurt me through your eyes, so I can see their brokenness and understand how that brokenness may have led them to hurt me. Give me an open heart and a willingness to listen and understand. If reconciliation is wise and if everyone is willing, please help us reconcile and build healthy new relationships with each other. Help us move forward with mutual respect and a shared commitment to healing and restoration. If reconciliation isn’t wise or possible, give me your perfect peace to help me end my toxic relationships and move forward by myself into a better future. Thank you, my loving God. Amen. 

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  • sad man hugging another man as friends

    5. Prayer for healing and transformation.

    Dear God, please heal the toxic people I know and transform their lives for the better. Only you can soften their hearts and bring positive change to their lives. You are the God of miracles, the one who heals the brokenhearted and binds up their wounds, as Psalm 147:3 points out. I place my trust in you, God. I believe that you are able to bring healing and restoration to even the most broken relationships. God, you say in 2 Corinthians 7:10: “Godly sorrow brings repentance that leads to salvation and leaves no regret…”.

    Please convict the toxic people I know of their sinful actions and lead them to repentance. Open their eyes to see the painful impact of their toxic words and actions. Give them the humility to seek forgiveness and reconciliation. Break down the walls of pride and defensiveness that hinder their ability to receive your love. Touch their hearts with your transforming power and bring about a deep inner healing that only you can provide. Heal the wounds and traumas that may be driving their toxic behavior, and replace them with the peace and joy that come from you. May they discover the wonder of your work in their lives, so they’ll be inspired to trust you in deeper ways. Please keep working in their lives constantly through your Holy Spirit, meeting them where they are and drawing them closer to you. God, I also pray for my own healing and transformation as I deal with these challenging relationships. Please heal the wounds that I carry from past pain and give me the strength to forgive those who have wronged me. Help me to release the burden of resentment and bitterness, and to embrace the freedom that comes from extending forgiveness and grace. Thank you for healing us all, wonderful Father. Amen. 

    In our fallen world that’s full of pain, encountering toxic relationships is an inevitable reality. However, God calls us to respond to toxic people with compassion and wisdom. God will send his love flowing through our lives to others – no matter how challenging our relationships with them may be. Through prayer, we can find strength, guidance, and healing for ourselves and for the toxic people in our lives. So, let’s pray regularly for the toxic people we know, and look forward to the positive changes God will make happen in our relationships with them.

    Photo Credit: ©GettyImages/Sarah Mason 


    headshot of author Whitney HoplerWhitney Hopler helps people discover God's wonder and experience awe. She is the author of several books, including the nonfiction books Wake Up to Wonder and Wonder Through the Year: A Daily Devotional for Every Year, and the young adult novel Dream Factory. Whitney has served as an editor at leading media organizations, including Crosswalk.com, The Salvation Army USA’s national publications, and Dotdash.com (where she produced a popular channel on angels and miracles). She currently leads the communications work at George Mason University’s Center for the Advancement of Well-Being. Connect with Whitney on her website at www.whitneyhopler.com, on Facebook, and on  X/Twitter.